Research progress on the mechanism and countermeasures of acquired EGFR resistance

Epidermal growth factor receptor (EGFR) -tyrosine kinase inhibitors (TKI) have transformed traditional cancer treatment and brought good news to patients with non-small cell lung cancer. However, drug resistance problems arise one after another. Based on further exploration of the mechanism EGFR corresponding therapeutic strategies, author reviewed relevant literature, classified summarized it, providing ideas for solving clinical problem hope tumor patients.